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Patent Searching and Data

Document Type and Number:
Japanese Patent JP2007525990
Kind Code:
The invention relates to isolated mesenchymal stromal stem cell (MSSC) that has been differentiated in vitro towards, or to, an intervertebral disc (IVD) cell phenotype for use as medicaments. The cells may be used to treat spinal conditions characterized by degeneration of the intervertebral disc. The cells may also be genetically transformed with an exogenous gene coding for a protein that reduces degeneration of an intervertebral disc.

Fremont Anthony John
Hoyland Judith A
Le-M Christine
Richardson Stephen
Application Number:
Publication Date:
September 13, 2007
Filing Date:
February 25, 2005
Export Citation:
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The University of Manchester
International Classes:
C12N5/10; A61K35/14; A61K35/28; A61K35/32; A61K45/00; A61P19/00; A61P25/04; C12N5/071; C12N15/09; A61K35/12
Other References:
JPN6010067687, International Society for the Study of the Lumbar Spine (2003) 30th annual meeting, (abstruct #26)
JPN6010067688, J.Jpn.Orthop. Assoc., vol.76(8), p.S905, 1−B−S4−4 (2002)
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama