脊髄状態の治療 - The University of Manchester

Title:

脊髄状態の治療

Document Type and Number:

Japanese Patent JP2007525990

Kind Code:

A

Abstract:

The invention relates to isolated mesenchymal stromal stem cell (MSSC) that has been differentiated in vitro towards, or to, an intervertebral disc (IVD) cell phenotype for use as medicaments. The cells may be used to treat spinal conditions characterized by degeneration of the intervertebral disc. The cells may also be genetically transformed with an exogenous gene coding for a protein that reduces degeneration of an intervertebral disc.

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Inventors:

Fremont Anthony John
Hoyland Judith A
Le-M Christine
Richardson Stephen

Application Number:

JP2007501337A

Publication Date:

September 13, 2007

Filing Date:

February 25, 2005

Export Citation:

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Assignee:

The University of Manchester

International Classes:

C12N5/10; A61K35/14; A61K35/28; A61K35/32; A61K45/00; A61P19/00; A61P25/04; C12N5/071; C12N15/09; A61K35/12

Other References:

JPN6010067687, Ｉｎｔｅｒｎａｔｉｏｎａｌ　Ｓｏｃｉｅｔｙ　ｆｏｒ　ｔｈｅ　Ｓｔｕｄｙ　ｏｆ　ｔｈｅ　Ｌｕｍｂａｒ　Ｓｐｉｎｅ　（２００３）　３０ｔｈ　ａｎｎｕａｌ　ｍｅｅｔｉｎｇ，　（ａｂｓｔｒｕｃｔ　＃２６）
JPN6010067688, Ｊ．Ｊｐｎ．Ｏｒｔｈｏｐ．　Ａｓｓｏｃ．，　ｖｏｌ．７６（８），　ｐ．Ｓ９０５，　１−Ｂ−Ｓ４−４　（２００２）

Attorney, Agent or Firm:

Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama

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