Title:
補体C5a受容体モジュレーターを使用する神経疾患の治療
Document Type and Number:
Japanese Patent JP2007530454
Kind Code:
A
Abstract:
This invention relates to the treatment of neurological conditions with novel cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of C5a receptors. The compounds preferably act as antagonists of the C5a receptor, and are active against C5a receptors on polymorphonuclear leukocytes, monocytes, lymphocytes and/or macrophages. In a preferred form of the invention the neurological conditions are neurodegenerative diseases, neuroimmunological disorders, diseases arising from dysfunction of the blood brain barrier, and stroke.
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Inventors:
Trent Martin Woodruff
Stephen Maxwell Taylor
Stephen Maxwell Taylor
Application Number:
JP2007504211A
Publication Date:
November 01, 2007
Filing Date:
March 21, 2005
Export Citation:
Assignee:
Promix Pty Limited
International Classes:
A61K38/00; A61K38/12; A61K39/395; A61K45/00; A61P9/10; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P43/00
Foreign References:
| EP1308438A1 | 2003-05-07 | |||
| WO2003033528A1 | 2003-04-24 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro