Title:
プラゾール類誘導体及びその塩と用途
Document Type and Number:
Japanese Patent JP2008514653
Kind Code:
A
Abstract:
The present invention relates to derivatives of compounds (formula (I) or (II)) and their salts, wherein R 1 represents lower alkyl or the lower alkyl substituted by halogen atoms, R 2 represents straight-chain or branched-chain alkyl containing 1-4 carbon atoms and R 3 represents hydrogen atom or alkali metals such as lithium, sodium, potassium or alkaline-earth metals such as magnesium and calcium. In the present invention, compounds with formula (I) or (II) and their derivatives or salts thereof acceptable in pharmacy and pharmacology can remarkably improve the effectiveness of anti-ulcer in alimentary tract, weakly inhibit gastric acid secretion, reduce the risk of stomach cancer and have excellent bio-availability and other in-vive pharmacokinetic characteristics.
Inventors:
Bell Hui
Lu Aifeng
Lu Aifeng
Application Number:
JP2007533852A
Publication Date:
May 08, 2008
Filing Date:
September 23, 2005
Export Citation:
Assignee:
Jiang Su Aomori Pharmaceutical Business Cross Division Co., Ltd.
International Classes:
C07D401/12; A61K31/437; A61K31/4439; A61P1/04; A61P31/04; C07D471/04
Attorney, Agent or Firm:
Yasuo Itaya