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Title:
妊娠に関連する化合物の投与による多能性幹細胞の増殖の刺激
Document Type and Number:
Japanese Patent JP2008515818
Kind Code:
A
Abstract:
The present invention relates to a composition comprising pregnancy related compounds selected from the group consisting of HCG and LH for use for treatment of a disease or condition characterized by damaged or diseased heart cells in a human.

Inventors:
Tucker, joseph
Application Number:
JP2007534984A
Publication Date:
May 15, 2008
Filing Date:
October 07, 2005
Export Citation:
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Assignee:
Stem Cell Therapeutics Corporation
International Classes:
A61K38/22; A61K38/24; A61P1/16; A61P9/00; A61P13/12
Domestic Patent References:
JP2003501081A2003-01-14
JP2004135625A2004-05-13
Foreign References:
WO2003024472A22003-03-27
WO2003018782A22003-03-06
WO2002005811A12002-01-24
WO2003103611A22003-12-18
Other References:
JPN6011032120; SHINGO,T. et al: 'Pregnancy-stimulated neurogenesis in the adult female forebrain mediated by prolactin' Science Vol.299, No.5603, 2003, p.117-20
JPN6011032123; OGUETA,S. et al: 'Prolactin is a component of the human synovial liquid and modulates the growth and chondrogenic diff' Mol Cell Endocrinol Vol.190, No.1-2, 2002, p.51-63
JPN6011032125; 坪田一男ら: '涙腺の分化増殖機構の解明と再生医療への応用' 平成14年度 総括・分担研究報告書 平成14年度 総括・分担研究報告書, 2003, 1-8
JPN6011032127; AL-HADER,A.A. et al: 'Neurons from fetal rat brains contain functional luteinizing hormone/chorionic gonadotropin receptor' Biol Reprod Vol.56, No.5, 1997, p.1071-6
JPN6011032130; 菅野雅人ら: '肝幹細胞研究の現状 肝幹細胞 肝臓における多能性幹細胞' 肝胆すい Vol.46, No.3, 2003, 319-26
JPN6011032134; 菱川慶一: '腎臓内科学 腎由来体性幹細胞による腎再生' 週刊医学のあゆみ Vol.204, No.11, 2003, 815-6
JPN6011032138; SAKAGUCHI,K. et al: 'Differential regulation of prolactin receptor mRNA expression in rat liver and kidney by testosteron' J Endocrinol Vol.143, No.2, 1994, p.383-92
JPN6011032139; DI,C.A. et al: 'Characterization of prolactin receptor in human brain and choroid plexus' Brain Res Vol.570, No.1-2, 1992, p.341-6
JPN6011032141; OUHTIT,A. et al: 'Visualization of gene expression of short and long forms of prolactin receptor in the rat' Endocrinology Vol.133, No.1, 1993, p.135-44
JPN6011032157; BERLANGA,J.J. et al: 'Prolactin receptor is associated with c-src kinase in rat liver' Mol Endocrinol Vol.9, No.11, 1995, p.1461-7
JPN6011032146; MOUNTJOY,K. et al: 'Prolactin receptors in the rat kidney' J Endocrinol Vol.87, No.1, 1980, p.47-54
JPN6011032147; LEI,Z.M. et al: 'Novel expression of human chorionic gonadotropin/luteinizing hormone receptor gene in brain' Endocrinology Vol.132, No.5, 1993, p.2262-70
JPN6011032150; TSAI-MORRIS,C.H. et al: 'Structural organization of the rat luteinizing hormone (LH) receptor gene' J Biol Chem Vol.266, No.17, 1991, p.11355-9
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita