Title:
BACE阻害剤として有用な大環状化合物
Document Type and Number:
Japanese Patent JP2008526913
Kind Code:
A
Abstract:
The invention relates to novel macrocyclic compounds of the formula (I), in which all of the variables are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
Inventors:
Claudia Beccart
Andreas Lerchner
Reiner Machuer
Heinrich Rüger
Marina Tintelknot-Bromley
Seem Jacob Fernstra
Andreas Lerchner
Reiner Machuer
Heinrich Rüger
Marina Tintelknot-Bromley
Seem Jacob Fernstra
Application Number:
JP2007550765A
Publication Date:
July 24, 2008
Filing Date:
January 13, 2006
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D471/08; A61K31/439; A61P9/00; A61P25/00; A61P43/00; C07B61/00
Domestic Patent References:
| JP2009513510A | 2009-04-02 | |||
| JP2007510002A | 2007-04-19 | |||
| JP2007502278A | 2007-02-08 | |||
| JP2008508289A | 2008-03-21 | |||
| JP2008526912A | 2008-07-24 | |||
| JP2004534064A | 2004-11-11 |
Foreign References:
| WO2004062625A2 | 2004-07-29 | |||
| WO2002100399A1 | 2002-12-19 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi