Title:
ATP結合カセットトランスポーターのモジュレーター
Document Type and Number:
Japanese Patent JP2008533045
Kind Code:
A
Abstract:
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Inventors:
Hadida, Lua Sara
Hazlewood, Anna Earl.
Gluten Hoyce, Peter Dee. Jay.
Butterfly, chinran
Hazlewood, Anna Earl.
Gluten Hoyce, Peter Dee. Jay.
Butterfly, chinran
Application Number:
JP2008501022A
Publication Date:
August 21, 2008
Filing Date:
March 13, 2006
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D209/12; A61K31/404; A61K31/4439; A61K31/454; A61K31/4725; A61K31/496; A61P3/06; C07D401/12; A61P3/00; A61P3/10; A61P5/00; A61P5/18; A61P7/12; A61P11/00; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/02
Domestic Patent References:
| JP2001517707A | 2001-10-09 | |||
| JP2000505098A | 2000-04-25 | |||
| JP2003519137A | 2003-06-17 | |||
| JP2007505127A | 2007-03-08 | |||
| JP2004513882A | 2004-05-13 | |||
| JP2001517707A | 2001-10-09 |
Foreign References:
| WO2003041644A2 | 2003-05-22 | |||
| US2825734A | 1958-03-04 | |||
| US20030181482A1 | 2003-09-25 | |||
| WO2004065356A1 | 2004-08-05 | |||
| WO1999051224A1 | 1999-10-14 |
Other References:
JPN5008001661; ＤＲＵＧＳ ＯＦ ＴＨＥ ＦＵＴＵＲＥ Ｖ２７ Ｎ１２, 20021201, Ｐ１１９５-１２３２, ＰＲＯＵＳ ＳＣＩＥＮＣＥ，Ｓ．Ａ．
JPN6013002099; ＲＯＳＳＩ，Ｐ．Ｆ． ｅｔ ａｌ．: '３-Ｉｎｄｏｌｅｇｌｙｏｘｙｌｉｃ ａｃｉｄ． Ｒｅａｃｔｉｏｎ ｗｉｔｈ ａｌｋｙｌ ａｎｄ ａｒｙｌｍｉｎｅｓ' Ａｎｎａｌｉ ｄｉ Ｃｈｉｍｉｃａ（Ｒｏｍｅ， Ｉｔａｌｙ） Ｖｏｌ．５１, 1961, ｐ６４-７０
JPN6013002099; ＲＯＳＳＩ，Ｐ．Ｆ． ｅｔ ａｌ．: '３-Ｉｎｄｏｌｅｇｌｙｏｘｙｌｉｃ ａｃｉｄ． Ｒｅａｃｔｉｏｎ ｗｉｔｈ ａｌｋｙｌ ａｎｄ ａｒｙｌｍｉｎｅｓ' Ａｎｎａｌｉ ｄｉ Ｃｈｉｍｉｃａ（Ｒｏｍｅ， Ｉｔａｌｙ） Ｖｏｌ．５１, 1961, ｐ６４-７０
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita