Title:
角膜組織を生体外保存するための組成物および方法
Document Type and Number:
Japanese Patent JP2008538752
Kind Code:
A
Abstract:
A corneal storage solution which maintains cell density and cell viability of corneas stored in vitro for a period of greater than four days up to about two weeks is provided. The solution contains a buffered, balanced, nutrient and electrolyte aqueous solution, at least one colloidal osmotic agent, a phenolic antioxidant compound, a non-lactate-generating substrate, a thiol-containing compound, insulin, and at least one antibiotic. A method for in vitro storage and preservation of the viability of human corneal endothelial cells for subsequent use includes the steps of removing a cornea from an eye globe and placing the cornea in the above corneal storage solution.
Inventors:
Zol, David, Bee.
Smith, Teresita, M.
Lewis-White, Ines, Ay.
Smith, Teresita, M.
Lewis-White, Ines, Ay.
Application Number:
JP2008506541A
Publication Date:
November 06, 2008
Filing Date:
April 06, 2006
Export Citation:
Assignee:
Creo Cosmetics and Pharmaceutical Company LLC
International Classes:
A01N1/02
Attorney, Agent or Firm:
Kazuyoshi Tsujimoto
Nozomi Tsujimoto
Taneichi Jie
Nozomi Tsujimoto
Taneichi Jie