Title:
アシッドポンプアンタゴニストとしてのクロマン置換ベンゾイミダゾール誘導体
Document Type and Number:
Japanese Patent JP2008543824
Kind Code:
A
Abstract:
This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5 and R6, R7, R8 and R9 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
More Like This:
Inventors:
Hiroki Koike
Sakiko Sakakibara
Sakiko Sakakibara
Application Number:
JP2008516435A
Publication Date:
December 04, 2008
Filing Date:
June 02, 2006
Export Citation:
Assignee:
Pfizer Japan Inc
International Classes:
C07D405/12; A61K31/4184; A61K31/496; A61P1/00; A61P1/04; A61P11/00; A61P11/06; A61P43/00; C07D405/14
Attorney, Agent or Firm:
Yoshinobu Murofushi