Title:
製薬学的使用のためのマラチオンの調製方法
Document Type and Number:
Japanese Patent JP2009500422
Kind Code:
A
Abstract:
The present invention provides a process for preparing a highly pure form of malathion having a reduced level of toxic impurities. In addition, the malathion prepared by the process of this invention is storage stable. The level of toxic impurities in the malathion, e.g., isomalathion, O,O,S-trimethyl phosphorodithioate (MeOOSPS), O,O,S-trimethyl phosphorothioate (MeOOSPO), O,S,S-trimethyl phosphorodithioate (MeOSSPO), malaoxon, isomalathion, diethyl fumarate, methyl malathion, dimethyl malathion, O,O-methyl,ethyl-S-(1,2-dicarboethoxy)ethyl-phosphorodithioate are lower than that of any other commercial preparation of malathion that may be used for pharmaceutical purposes.
Inventors:
Gutman Daniela
By Dussi Wael
By Dussi Wael
Application Number:
JP2008520372A
Publication Date:
January 08, 2009
Filing Date:
July 06, 2006
Export Citation:
Assignee:
Tarlo Pharmaceuticals North America, Inc.
International Classes:
C07F9/165
Domestic Patent References:
| JPS50106927A | 1975-08-22 | |||
| JPS265930B1 | ||||
| JPS5625192A | 1981-03-10 | |||
| JPS4429647B1 | ||||
| JPS265930B1 | ||||
| JPS50106927A | 1975-08-22 | |||
| JPS5625192A | 1981-03-10 | |||
| JPS4429647B1 |
Foreign References:
| US3463841A | 1969-08-26 | |||
| US4367180A | 1983-01-04 | |||
| US3440305A | 1969-04-22 | |||
| US3463841A | 1969-08-26 | |||
| US4367180A | 1983-01-04 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama