Title:
炎症性疾患および痛みの治療
Document Type and Number:
Japanese Patent JP2009501149
Kind Code:
A
Abstract:
A compound that is useful for the treatment or prevention of a condition such as pain, that is associated with T-cell proliferation or that is mediated by pro- and/or anti-inflammatory cytokines, is of formula (I) wherein R1 is aryl or heteroaryl optionally substituted with R5; R2 is H, alkyl or CH2OH and can be part of a ring with R4; R3 is H, alkyl or CH2OH and can be part of a ring with R4; R4 is H or alkyl or CH2 (when forming part of a ring with R2 or R3); and R5 is alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, F, Cl, Br, I, NH2, NHCHO, NHCONH2, NHSO2alkyl, CONH2, SOMe, CH2OH or OCONalkyl2; or a salt thereof.
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Inventors:
Baxter, Andrew Douglas
Line, Michael Harvey
Bannister, Robin Mark
La Stella, Elena
Line, Michael Harvey
Bannister, Robin Mark
La Stella, Elena
Application Number:
JP2008518968A
Publication Date:
January 15, 2009
Filing Date:
June 30, 2006
Export Citation:
Assignee:
Sosei R&D Limited
International Classes:
A61K31/137; A61K31/133; A61K45/00; A61P1/02; A61P1/04; A61P1/16; A61P3/10; A61P5/38; A61P5/48; A61P7/10; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P15/00; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P25/04; A61P25/06; A61P25/16; A61P25/28; A61P29/00; A61P37/02; A61P37/08; C07C215/30; C07C215/68
Attorney, Agent or Firm:
Hidekazu Miyoshi
Masakazu Ito
Yuko Hara
Masakazu Ito
Yuko Hara