Title:
VDCCガンマ-8イオンチャネル
Document Type and Number:
Japanese Patent JP2009506765
Kind Code:
A
Abstract:
VDCC gamma-8 polypeptides comprising the amino acid sequence shown in SEQ ID NO. 3, SEQ ID NO. 5 or SEQ ID NO: 7, and homologues, variants and derivatives thereof are provided. Nucleic acids capable of encoding VDCC gamma-8 polypeptide are also disclosed, in particular, those comprising the nucleic acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID NO. 4 or SEQ ID NO: 6. These polypeptides and polynucleotides are implicated in mental illness and are useful in screening for therapeutic agents useful in treating mental illness.
Inventors:
John Dixon
Justin Powell
Malcolm Sharedown
Nicola Bryce
Jennifer marie horwood
Isabelle Marinji
Haiping Liu
Cock Si Fu
Justin Powell
Malcolm Sharedown
Nicola Bryce
Jennifer marie horwood
Isabelle Marinji
Haiping Liu
Cock Si Fu
Application Number:
JP2008528582A
Publication Date:
February 19, 2009
Filing Date:
September 04, 2006
Export Citation:
Assignee:
Takeda Cambridge Limited
International Classes:
C12Q1/02; A01K67/027; A61K31/711; A61K45/00; A61K48/00; A61P25/00; A61P25/08; A61P25/18; A61P25/24; C07K14/705; C12Q1/68; G01N33/15; G01N33/50; G01N33/68; C12N15/09
Foreign References:
| WO2003083046A2 | 2003-10-09 | |||
| WO2001021791A2 | 2001-03-29 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro