Title:
神経保護薬
Document Type and Number:
Japanese Patent JP2009507848
Kind Code:
A
Abstract:
Methods of protecting cells against cytotoxic insults are provided. The methods involve administering a composition including a CpG oligonucleotide to a subject. The methods are applicable to the protection of neural and non-neural cells. For example, methods of protecting a neural cell against excitotoxic brain injury are provided. Methods for preparing medicaments for the prophylactic treatment of excitotoxic injury, ischemia and/or hypoxia are also provided. Also provided are compositions for use in the described methods.
Inventors:
Stenzel-Pule Mary
Stevens Susan
Stevens Susan
Application Number:
JP2008530181A
Publication Date:
February 26, 2009
Filing Date:
September 08, 2006
Export Citation:
Assignee:
Oregon Health and Science University
International Classes:
A61K31/7088; A61K31/711; A61P1/16; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P21/00; A61P25/00; A61P25/08; A61P25/28; A61P37/00; A61P41/00; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue