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Title:
ヒスタミンH3アンタゴニストとして有用な、1-[[1-[(2-アミノ-6-メチル-4-ピリジニル)メチル]-4-フルオロ-4-ピペリジニル]カルボニル]-4-[2-(2-ピリジニル)-3H-イミダゾ[4,5-b]ピリジン-3-イル]ピペリジン
Document Type and Number:
Japanese Patent JP2009508958
Kind Code:
A
Abstract:
The present invention discloses the compound of Formula I and pharmaceutically acceptable salts and solvates thereof. The invention also relates to pharmaceutical compositions comprising the Compound of Formula I and its use in treating obesity, metabolic syndrome, diabetes, hepatic lipidosis or nonalcoholic fatty liver disease. The invention also relates to the use of a combination of the Compound of Formula I with additional therapeutic agents for treating obesity, metabolic syndrome, diabetes, hepatic lipidosis or nonalcoholic fatty liver disease.

Inventors:
Delera Lewis, Maniel
Aslanian, Robert G.
Berlin, Michael Wye.
McCormick, Kevin Dee.
Cerry, Chandler S.
Application Number:
JP2008532314A
Publication Date:
March 05, 2009
Filing Date:
September 19, 2006
Export Citation:
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Assignee:
Schering Corporation
International Classes:
C07D471/04; A61K31/4545; A61K45/00; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P43/00
Foreign References:
WO2003088967A12003-10-30
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita