Title:
キナーゼ拮抗剤
Document Type and Number:
Japanese Patent JP2009532476
Kind Code:
A
Abstract:
The present invention provides methods for identifying PI3-Kinase antagonists and antagonists identified by said method.
Inventors:
Shokart, Keban M.
Knight, Zachary A.
Upsel, Beth
Knight, Zachary A.
Upsel, Beth
Application Number:
JP2009504278A
Publication Date:
September 10, 2009
Filing Date:
April 04, 2007
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C07D487/04; A61K31/519; A61P19/08; A61P35/00; A61P43/00
Domestic Patent References:
| JP2002534524A | 2002-10-15 | |||
| JP2002503953A | 2002-02-05 | |||
| JP2003509428A | 2003-03-11 |
Foreign References:
| US20050085472A1 | 2005-04-21 | |||
| US20030180924A1 | 2003-09-25 | |||
| US5593997A | 1997-01-14 | |||
| WO2007126841A2 | 2007-11-08 |
Other References:
JPN5009003863; ＴＡＮＡＫＡ: ＰＬＯＳ ＢＩＯＬＯＧＹ Ｖ３ Ｎ５, 200505, Ｐ０７６４-０７７６
JPN6012056724; Ｋｒｅｕｔｚｂｅｒｇｅｒ， Ａｌｆｒｅｄ； Ｗｉｅｄｅｍａｎｎ， Ｄａｇｍａｒ: '５-Ｓｕｂｓｔｉｔｕｔｅｄ ４-ａｍｉｎｏｐｙｒｉｍｉｄｉｎｅｓ ｂｙ ａｍｉｎｏｍｅｔｈｉｎｙｌａｔｉｏｎ ｏｆ ａｃｅｔｏｎｉｔｒｉｌｅｓ' Ｊｕｓｔｕｓ Ｌｉｅｂｉｇｓ Ａｎｎａｌｅｎ ｄｅｒ Ｃｈｅｍｉｅ （４）, 1977, ５３７-４４
JPN6012056725; Ｈａｎｅｆｅｌｄ， Ｕｌｆ； Ｒｅｅｓ， Ｃｈａｒｌｅｓ Ｗ．； Ｗｈｉｔｅ， Ａｎｄｒｅｗ Ｊ． Ｐ．； Ｗｉｌｌｉａｍｓ， Ｄａｖｉｄ Ｊ．: 'Ｏｎｅ-ｐｏｔ ｓｙｎｔｈｅｓｉｓ ｏｆ ｔｅｔｒａｓｕｂｓｔｉｔｕｔｅｄ ｐｙｒａｚｏｌｅｓ - ｐｒｏｏｆ ｏｆ ｒｅｇｉｏｃｈｅｍｉｓｔｒｙ' Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ， Ｐｅｒｋｉｎ Ｔｒａｎｓａｃｔｉｏｎｓ １： Ｏｒｇａｎｉｃ ａｎｄ Ｂｉｏ-Ｏｒｇａｎｉｃ Ｃｈｅｍｉｓｔｒｙ （１３）, 1996, １５４５-１５５２
JPN6012056724; Ｋｒｅｕｔｚｂｅｒｇｅｒ， Ａｌｆｒｅｄ； Ｗｉｅｄｅｍａｎｎ， Ｄａｇｍａｒ: '５-Ｓｕｂｓｔｉｔｕｔｅｄ ４-ａｍｉｎｏｐｙｒｉｍｉｄｉｎｅｓ ｂｙ ａｍｉｎｏｍｅｔｈｉｎｙｌａｔｉｏｎ ｏｆ ａｃｅｔｏｎｉｔｒｉｌｅｓ' Ｊｕｓｔｕｓ Ｌｉｅｂｉｇｓ Ａｎｎａｌｅｎ ｄｅｒ Ｃｈｅｍｉｅ （４）, 1977, ５３７-４４
JPN6012056725; Ｈａｎｅｆｅｌｄ， Ｕｌｆ； Ｒｅｅｓ， Ｃｈａｒｌｅｓ Ｗ．； Ｗｈｉｔｅ， Ａｎｄｒｅｗ Ｊ． Ｐ．； Ｗｉｌｌｉａｍｓ， Ｄａｖｉｄ Ｊ．: 'Ｏｎｅ-ｐｏｔ ｓｙｎｔｈｅｓｉｓ ｏｆ ｔｅｔｒａｓｕｂｓｔｉｔｕｔｅｄ ｐｙｒａｚｏｌｅｓ - ｐｒｏｏｆ ｏｆ ｒｅｇｉｏｃｈｅｍｉｓｔｒｙ' Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ， Ｐｅｒｋｉｎ Ｔｒａｎｓａｃｔｉｏｎｓ １： Ｏｒｇａｎｉｃ ａｎｄ Ｂｉｏ-Ｏｒｇａｎｉｃ Ｃｈｅｍｉｓｔｒｙ （１３）, 1996, １５４５-１５５２
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita