Title:
シグマ(σ)受容体を阻害するスピロ[ベンゾピラン]誘導体またはスピロ[ベンゾフラン]誘導体
Document Type and Number:
Japanese Patent JP2009534344
Kind Code:
A
Abstract:
The present invention relates to compounds (I) having pharmacological activity towards the sigma (Ã) receptor, and more particularly to spiro[benzopyran] or spiro[benzofuran] derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis.
wherein
m is selected from 1 or 2, p is selected from 1 or 2, and m + p is either 2 or 3;
n is selected from 0 or 1;
R 1 , R 2 are as defined in the application.
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Inventors:
Bunsch, Bernard
Application Number:
JP2009505798A
Publication Date:
September 24, 2009
Filing Date:
April 23, 2007
Export Citation:
Assignee:
Laboratorios del. Dr. Estave, Ese. A.
International Classes:
C07D491/107; A61K31/407; A61K31/4178; A61K31/438; A61P1/04; A61P1/12; A61P3/04; A61P3/06; A61P9/06; A61P9/10; A61P9/12; A61P19/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/18; A61P25/24; A61P25/28; A61P25/32; A61P25/34; A61P25/36; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D491/20
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita