Title:
C-KITキナーゼ阻害法
Document Type and Number:
Japanese Patent JP2009534418
Kind Code:
A
Abstract:
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a ompound of the present invention:
or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
Inventors:
Karl Earl
Valentine, Serie Kay
Chien, jinshieng
Sanega Kay, Megara
Wall, Mark Jei
Wilson, Kenneth J.A.
Rudolf, M. Jonathan
Death Jar Race, Rene El
Molloy, Christopher Jay
Karl Elle, Mansei
Valentine, Serie Kay
Chien, jinshieng
Sanega Kay, Megara
Wall, Mark Jei
Wilson, Kenneth J.A.
Rudolf, M. Jonathan
Death Jar Race, Rene El
Molloy, Christopher Jay
Karl Elle, Mansei
Application Number:
JP2009506778A
Publication Date:
September 24, 2009
Filing Date:
April 19, 2007
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D307/56; A61K31/4178; A61K31/454; A61K31/496; A61K31/5377; A61K45/00; A61P3/10; A61P9/00; A61P9/10; A61P17/06; A61P19/02; A61P25/18; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P43/00; C07D401/12; C07D401/14; C07D407/12; C07D409/12; C07D409/14
Domestic Patent References:
| JP5046950B2 | 2012-10-10 | |||
| JP2009511628A | 2009-03-19 | |||
| JP2009534405A | 2009-09-24 | |||
| JP2009534406A | 2009-09-24 | |||
| JP2009534407A | 2009-09-24 | |||
| JP2009534380A | 2009-09-24 | |||
| JP5089681B2 | 2012-12-05 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office