Title:
B細胞障害の治療における免疫グロブリン結合細胞表面決定基
Document Type and Number:
Japanese Patent JP2009536217
Kind Code:
A
Abstract:
The present invention provides methods, compositions and vaccines for specifically targeting immunoglobulin associated cell-surface determinants that are not shed into the blood of a host. In some cases, the immunoglobulin associated cell-surface determinants will be involved in various B-cell disorders. The methods involve administering an IACSD targeting element to a B-cell. The method can employ treating an individual with a B-cell associated disorder by administering an effective amount of an IACSD targeting preparation. The compositions include isolated antibodies where the antibodies associate with an immunoglobulin associated cell-surface determinants. The invention also includes vaccines that immunize against immunoglobulin associated cell-surface determinants.
Inventors:
Welt, Sydney
Costial, David, A.
Costial, David, A.
Application Number:
JP2009510082A
Publication Date:
October 08, 2009
Filing Date:
May 03, 2007
Export Citation:
Assignee:
Guthrie Foundation for Education and Research
International Classes:
A61K39/395; A61K45/00; A61K51/00; A61P1/04; A61P1/16; A61P3/10; A61P5/14; A61P7/04; A61P7/06; A61P9/10; A61P11/06; A61P17/00; A61P17/06; A61P17/08; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Ikeda adult
Masakazu Noda
Ikeda adult