無差別HER-2/NeuCD4T細胞エピトープ

Title:

無差別HER-2/NeuCD4T細胞エピトープ

Document Type and Number:

Japanese Patent JP2010501160

Kind Code:

A

Abstract:

The present invention relates to the discovery of novel T cell epitopes of the human HER-2/Neu protein that is promiscuous for at least 25 different HLA-DR alleles. The invention also relates to compositions that contain one of the novel epitopes or a fusion peptide of such a epitope and a heterologous polypeptide. Further disclosed herein is the use of the epitopes or their fusion peptides, and compositions containing the epitopes or their fusion peptides.

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Inventors:

Warlan, Jamie Bee.
Jones, Lori.

Application Number:

JP2009524009A

Publication Date:

January 21, 2010

Filing Date:

August 10, 2007

Export Citation:

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Assignee:

Dendreon Corporation

International Classes:

C12N15/09; A61K39/00; A61K39/395; A61P35/00; C07K7/00; C07K14/535; C07K19/00; G01N33/53; G01N33/543; C07K14/705

Domestic Patent References:

JP2003529608A

2003-10-07

Foreign References:

WO2005007694A1	2005-01-27
EP1568373A2	2005-08-31
WO2006061253A2	2006-06-15
WO2005007694A1	2005-01-27

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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