Title:
脳ガンの処置又は予防のためのMTキナーゼ阻害剤の使用
Document Type and Number:
Japanese Patent JP2010507625
Kind Code:
A
Abstract:
The present invention is concerned with the finding that some the macrocyclic quinazoline derivative 4,6-ethanediylidenepyrimido[4,5-b][6,1,12]benzoxadiazacyclo-pentadecine, 17-bromo-8,9,10,11,12,13,14,19-octahydro-20-methoxy-13-methyl-, described as compound 22 in PCT publication WO2004/105765, is useful in the manufacture of a medicament for the treatment or prevention of a primary brain cancer or brain metastasis. It accordingly provides methods for treating, preventing, delaying or mitigating brain cancer, or for preventing or slowing proliferation of cells of brain origin.
Inventors:
Perera, Timothy Pietro Slen
Paige, Martin Jiyoung
Jean Nico, Michele Marie Francois
Frenu, Eddie Jean-Edgar
Paige, Martin Jiyoung
Jean Nico, Michele Marie Francois
Frenu, Eddie Jean-Edgar
Application Number:
JP2009533849A
Publication Date:
March 11, 2010
Filing Date:
October 25, 2007
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
A61K31/519; A61K31/175; A61K31/395; A61K45/00; A61P35/00; C07D498/08
Attorney, Agent or Firm:
Patent business corporation Odashima patent office