Title:
第Xa因子阻害剤としてのチオフェンカルボキサミド
Document Type and Number:
Japanese Patent JP2010515689
Kind Code:
A
Abstract:
The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
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Inventors:
Chu, Bin-Yang
Bower, Shawn M.
Chia, Chaochon Jay.
Song, Yong Hong
Probst, Gary Dee.
Chang, Yangcheng
Scarborough, Carroll
Bower, Shawn M.
Chia, Chaochon Jay.
Song, Yong Hong
Probst, Gary Dee.
Chang, Yangcheng
Scarborough, Carroll
Application Number:
JP2009544989A
Publication Date:
May 13, 2010
Filing Date:
January 04, 2008
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D401/10; A61K31/4178; A61K31/4192; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/522; A61K31/5377; A61K31/538; A61K31/55; A61K31/551; A61P7/02; A61P9/10; A61P43/00; C07D409/12; C07D409/14; C07D413/14; C07D473/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita