Title:
グルコキナーゼ活性化因子としての2,2,2-三置換アセトアミド誘導体、その方法及び薬学的応用
Document Type and Number:
Japanese Patent JP2010520195
Kind Code:
A
Abstract:
Compounds of the present disclosure are 2,2,2-tri-substituted acetamide derivatives of formula (I), its polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, useful as Glucokinase activator. Processes of their preparation are also described in the disclosure. The disclosure also describes method to characterize partial glucokinase activators.
Inventors:
Mukatia Kashin Ai.
Bunya Devnath
Dave Bhubabesh
Capcoty Govind S.
Basu S Jay
Chug Anita
Desidartha
Palais Ben Carty.
Bunya Devnath
Dave Bhubabesh
Capcoty Govind S.
Basu S Jay
Chug Anita
Desidartha
Palais Ben Carty.
Application Number:
JP2009551312A
Publication Date:
June 10, 2010
Filing Date:
February 25, 2008
Export Citation:
Assignee:
ADVINUS THERAPEUTICS PRIVATE LIMITED
International Classes:
C07D213/80; A61K31/41; A61K31/42; A61K31/426; A61K31/427; A61K31/428; A61K31/433; A61K31/44; A61K31/4439; A61K31/505; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P27/02; A61P43/00; C07D213/82; C07D239/42; C07D257/04; C07D261/14; C07D277/20; C07D277/46; C07D277/56; C07D277/82; C07D285/135; C07D417/12
Domestic Patent References:
| JPS61126071A | 1986-06-13 | |||
| JP2009522937A | 2009-06-11 | |||
| JP2006025403A | 2006-01-26 | |||
| JP2008115149A | 2008-05-22 | |||
| JP2009544755A | 2009-12-17 | |||
| JP2005525291A | 2005-08-25 | |||
| JP2003507329A | 2003-02-25 |
Foreign References:
| DE2924900A1 | 1981-01-22 | |||
| WO2008014199A2 | 2008-01-31 | |||
| WO2005123132A2 | 2005-12-29 | |||
| WO2006001750A1 | 2006-01-05 | |||
| WO2005033072A2 | 2005-04-14 |
Attorney, Agent or Firm:
Masaki Hirota