Title:
WEELキナーゼインヒビターとしてのジヒドロピラゾロピリミジノン誘導体の多形
Document Type and Number:
Japanese Patent JP2010525057
Kind Code:
A
Abstract:
The present invention relates to the crystalline forms of 2-allyl-1-[6-(I-hydroxy-1 methylethyl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one or a salt thereof, which are useful in the field of treatment of various cancers as a kinase inhibitor, especially as a Weel kinase inhibitor.
Inventors:
Masashi Kawasaki
Hiroo Mizuno
Toshihiro Sakamoto
Suzuki fair
McCune, Arlene, Yi
Hiroo Mizuno
Toshihiro Sakamoto
Suzuki fair
McCune, Arlene, Yi
Application Number:
JP2010506227A
Publication Date:
July 22, 2010
Filing Date:
April 22, 2008
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
Merck Sharp End Dome Corporation
Merck Sharp End Dome Corporation
International Classes:
C07D487/04; A61K31/519; A61K45/00; A61P35/00; A61P35/02
Foreign References:
| WO2003091255A1 | 2003-11-06 | |||
| WO2007126128A1 | 2007-11-08 | |||
| WO2003091255A1 | 2003-11-06 |
Attorney, Agent or Firm:
Kenji Ando
Yokoyama Isao
Yokoyama Isao