Title:
BMP-10活性を調整する方法および組成物
Document Type and Number:
Japanese Patent JP2010529041
Kind Code:
A
Abstract:
Methods and compositions for modulating cardiac, renal and vascular cell function and homeostasis using agonists and antagonists of BMP-10 are disclosed. In particular, methods for treating, preventing and/or diagnosing BMP-10-associated vascular, renal, fibrotic and cardiac conditions and/or disorders are disclosed. Screening methods for evaluating BMP-10 modulators, e.g., agonists and antagonists, are also disclosed.
Inventors:
Kathleen M. Shields
Debra Di Pitman
Jeffrey El Feldman
Robert Martinez
Christine Huard
Debra Di Pitman
Jeffrey El Feldman
Robert Martinez
Christine Huard
Application Number:
JP2010510534A
Publication Date:
August 26, 2010
Filing Date:
May 30, 2008
Export Citation:
Assignee:
Weiss LRC
International Classes:
A61K45/00; A61K31/7088; A61K31/713; A61K38/00; A61K39/395; A61K48/00; A61P3/06; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P17/06; A61P27/02; A61P29/00; A61P35/00
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Mizuhara Masahiro
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Mizuhara Masahiro