Title:
酵素特性を向上させたポリシアリルトランスフェラーゼの操作されたバージョン
Document Type and Number:
Japanese Patent JP2010529846
Kind Code:
A
Abstract:
The invention relates to poly-sialyltransferse polypeptides with enhanced solubility and activity and methods of using the poly-sialyltransferases for production of poly-sialylated end products, e.g., oligosaccharides, glycoproteins and glycolipids.
Inventors:
Wakersuk, Warren
Willis, Elizabeth
Gilbert, michel
Willis, Elizabeth
Gilbert, michel
Application Number:
JP2010511465A
Publication Date:
September 02, 2010
Filing Date:
June 13, 2008
Export Citation:
Assignee:
NATIONAL RESEARCH COUNCIL OF CANADA
International Classes:
C12N9/10; C12N15/09; C12P19/00; C12P19/04; C12P21/00
Other References:
JPN6013004668; Ｍｏｔｈｅｒｓｈｅｄ，Ｅ．Ａ． ｅｔ ａｌ．: 'Ｎｅｉｓｓｅｒｉａ ｍｅｎｉｎｇｉｔｉｄｉｓ ｓｔｒａｉｎ Ｍ１０１９ ｓｉａｌｙｌｔｒａｎｓｆｅｒａｓｅ （ｓｉａＤ） ｇｅｎｅ， ｐａｒｔｉａｌ ｃｄｓ' ＧｅｎＢａｎｋ： ＡＹ２３４１９２．１ ＬＯＣＵＳ： ＡＹ２３４１９２, 2004, ＶＥＲＳＩＯＮ： ＡＹ２３４１９２．１ ＧＩ：２９５６９６９０
JPN6013004671; Ｍｏｌｅｃｕｌａｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， （２０００）， Ｖｏｌ． １５， Ｎｏ． １， ｐ． ５１-６３
JPN6013004671; Ｍｏｌｅｃｕｌａｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， （２０００）， Ｖｏｌ． １５， Ｎｏ． １， ｐ． ５１-６３
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita