Title:
SNP遺伝子型に基づくQT延長の予測
Document Type and Number:
Japanese Patent JP2010538617
Kind Code:
A
Abstract:
The present invention relates to the prediction of QT prolongation following administration of a compound capable of increasing an individual's QT interval based on the individual's genotype at one or more single nucleotide polymorphism (SNP) loci and to the treatment of a patient based on such prediction.
Inventors:
Love dan, christian
Volpi, Simona
Rye Camel, Lewis
Mac, kendra, tomino
Heaton, carry, michelle
Volpi, Simona
Rye Camel, Lewis
Mac, kendra, tomino
Heaton, carry, michelle
Application Number:
JP2010524250A
Publication Date:
December 16, 2010
Filing Date:
September 10, 2008
Export Citation:
Assignee:
Vanda Pharmaceuticals, Inc.
International Classes:
C12Q1/68; A61K31/454; A61K45/00; A61P9/06; A61P25/18; A61P25/24; C12N15/09
Domestic Patent References:
| JP2005512576A | 2005-05-12 |
Foreign References:
| WO2006039663A2 | 2006-04-13 | |||
| WO2002022875A2 | 2002-03-21 |
Other References:
JPN6013029502; Ｄａｔａｂａｓｅ ｄｂＳＮＰ Ｓｈｏｒｔ Ｇｅｎｅｔｉｃ Ｖａｒｉａｔｉｏｎｓ ［ｏｎｌｉｎｅ］，Ｓｕｂｍｉｔｔｅｄ ＳＮＰ（ｓｓ） Ｄｅｔａｉｌｓ： ｓｓ１４５１０６２， ＲｅｆＳＮＰ（ｒｓ＃）：
JPN5007017119; ＪＡＩＮ，Ｋ．Ｋ: ＥＸＰＥＲＴ ＯＰＩＮＩＯＮ ＯＮ ＩＮＶＥＳＴＩＧＡＴＩＯＮＡＬ ＤＲＵＧＳ Ｖ９ Ｎ１２, 2000, Ｐ２９３５-２９４３
JPN6013029502; Ｄａｔａｂａｓｅ ｄｂＳＮＰ Ｓｈｏｒｔ Ｇｅｎｅｔｉｃ Ｖａｒｉａｔｉｏｎｓ ［ｏｎｌｉｎｅ］，Ｓｕｂｍｉｔｔｅｄ ＳＮＰ（ｓｓ） Ｄｅｔａｉｌｓ： ｓｓ１４５１０６２， ＲｅｆＳＮＰ（ｒｓ＃）：
JPN5007017119; ＪＡＩＮ，Ｋ．Ｋ: ＥＸＰＥＲＴ ＯＰＩＮＩＯＮ ＯＮ ＩＮＶＥＳＴＩＧＡＴＩＯＮＡＬ ＤＲＵＧＳ Ｖ９ Ｎ１２, 2000, Ｐ２９３５-２９４３
JPN6013029502; Ｄａｔａｂａｓｅ ｄｂＳＮＰ Ｓｈｏｒｔ Ｇｅｎｅｔｉｃ Ｖａｒｉａｔｉｏｎｓ ［ｏｎｌｉｎｅ］，Ｓｕｂｍｉｔｔｅｄ ＳＮＰ（ｓｓ） Ｄｅｔａｉｌｓ： ｓｓ１４５１０６２， ＲｅｆＳＮＰ（ｒｓ＃）：
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Ikeda adult
Masakazu Noda
Ikeda adult