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Title:
酸化還元反応によりモノクローナル抗体の結合特異性を改変させる方法
Document Type and Number:
Japanese Patent JP2010539232
Kind Code:
A
Abstract:
The binding specificity of a monoclonal antibody is altered by exposing the monoclonal antibody to an oxidizing agent or an electric potential.

Inventors:
McIntyre, John A
Application Number:
JP2010525802A
Publication Date:
December 16, 2010
Filing Date:
August 26, 2008
Export Citation:
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Assignee:
Redox-Reactive Reagents Limited Liability Company
International Classes:
C07K16/00; C12P21/08; G01N33/15; G01N33/50
Domestic Patent References:
JP2006526027A2006-11-16
Other References:
JPN6012021296; J. Biol. Chem., (2007.07), 282, [37], p.26696-26706
Attorney, Agent or Firm:
Kawamura Taku
Yousuke Fujimori
Seiji Tani