Title:
チエノピリミジン化合物類および組成物
Document Type and Number:
Japanese Patent JP2010540424
Kind Code:
A
Abstract:
Compounds of formula (I) are A2B wherein R1 and R2 are independently selected from hydrogen, or optionally substituted CrC6 alkyl, C1-C6alkoxy-(C1-C6)-alkyl, C3-C8 cycloalkyl, aryl, heteroaryl, aryl-(C1-C6)-alkyl, or heteroaryl-(C1-C6)-alkyl; or R−1 and R2 taken together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; R3 and R4 are independently selected from hydrogen, or optionally substituted C1-C6 alkyl, C1-C6 alkoxy-(C1-C6)-alkyl, C3-C8 cycloalkyl, aryl, heteroaryl, aryl-(C1-C6)-alkyl, or heteroaryl-C1-C6)-alkyl; or R3 and R4 taken together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; R5 and R6 are independently selected from hydrogen, C1-C6 alkyl, aryl, aryl-(C1-C6)-alkyl, —NHR7—N(—R8)—R9, —NH—(C═O)—R10, —(C═O)—NH—R11, —(C═O)—O—R12, or halo; and R7, R8, R9, R10, R−11, and R12 are independently selected from C1-C6 alkyl, aryl, aryl-(C1-C6)-alkyl and heteroaryl.
More Like This:
Inventors:
Alan Jordan
Bedford, Simon
Burghard, Klenke
Yule, Ian
Pula Neck, Carine
Bedford, Simon
Burghard, Klenke
Yule, Ian
Pula Neck, Carine
Application Number:
JP2010525426A
Publication Date:
December 24, 2010
Filing Date:
September 19, 2008
Export Citation:
Assignee:
VERNALIS R&D LIMITED
International Classes:
C07D495/04; A61K31/519; A61P1/04; A61P3/10; A61P11/00; A61P11/06; A61P13/00; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2007509947A | 2007-04-19 | |||
| JP2005525305A | 2005-08-25 | |||
| JP2003503504A | 2003-01-28 |
Foreign References:
| WO2007103776A2 | 2007-09-13 |
Attorney, Agent or Firm:
Shintaro Nogawa