Title:
アデノシンA1レセプターアンタゴニストとしての新規化合物
Document Type and Number:
Japanese Patent JP2010540615
Kind Code:
A
Abstract:
This compounds correspond to the formula (I), where: R1 represents and aryl or heteroaryl group optionally substituted by one or more substituents selected from the group consisting of halogen atoms, straight or branched optionally substituted lower alkyl, cycloalkyl, hydroxy, straight or branched, optionally substituted lower alkoxy, cyano, or —CO2R′, wherein R′ represents a hydrogen atom or a straight or branched, optionally substituted lower alkyl group; R2 represents a group selected from: a) a straight or branched lower alkyl group substituted by one or more carboxylic groups (—COOH) and optionally substituted by one or more halogen atoms; b) a cycloalkyl group substituted by one or more carboxylic groups (—COOH) and optionally substituted by one or more halogen atoms; c) a straight or branched alkylcycloalkyl or cycloalkylalkyl group substituted by one or more carboxylic groups (—COOH) and optionally substituted by one or more halogen atoms. Formula (I).
Inventors:
Gonzales Rio, Lichen
Camacho Gomez, Juan Albert
Camacho Gomez, Juan Albert
Application Number:
JP2010527561A
Publication Date:
December 24, 2010
Filing Date:
September 30, 2008
Export Citation:
Assignee:
Palobio Pharma, S. L.
International Classes:
C07D277/20; A61K31/426; A61K45/00; A61P9/06; A61P9/10; A61P9/12; A61P11/02; A61P11/06; A61P11/08; A61P13/12; A61P17/00; A61P17/04; A61P19/02; A61P25/22; A61P25/28; A61P37/08; A61P43/00; C07D277/56
Domestic Patent References:
| JP2005510508A | 2005-04-21 |
Foreign References:
| WO2007103550A2 | 2007-09-13 | |||
| WO2007116106A1 | 2007-10-18 |
Attorney, Agent or Firm:
▲吉▼川 俊雄