Title:
高脂血症または動脈硬化症などの疾患の処置に有用なCETP阻害剤としての4-ベンジルアミノ-1-カルボキシアシル-ピペリジン誘導体
Document Type and Number:
Japanese Patent JP2011503026
Kind Code:
A
Abstract:
The present invention provides a compound of formula (I):
wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP (cholesteryl ester transfer protein), and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
Inventors:
Moteto Mogi
Takeshi Yamada
Kayo Yasoshima
Toshio Kawanami
Umemura Ichiro
Iwaki Snow
Kin Hongbo
Imase Hidetomo
Takeshi Yamada
Kayo Yasoshima
Toshio Kawanami
Umemura Ichiro
Iwaki Snow
Kin Hongbo
Imase Hidetomo
Application Number:
JP2010532558A
Publication Date:
January 27, 2011
Filing Date:
November 03, 2008
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D401/12; A61K31/506; A61K31/5377; A61P3/04; A61P3/06; A61P3/10; A61P7/00; A61P7/02; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P43/00; C07D401/14; C07D413/14
Foreign References:
| WO2005095409A2 | 2005-10-13 | |||
| WO2006033002A1 | 2006-03-30 | |||
| WO2005033082A2 | 2005-04-14 | |||
| WO2008009435A1 | 2008-01-24 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai