Title:
スフィンゴシン-1-リン酸(S1P)受容体化合物
Document Type and Number:
Japanese Patent JP2011503168
Kind Code:
A
Abstract:
The invention relates to compounds, in particular 2-amino-3,4,5,-trisubstituted thiophenes, pharmaceutical compositions containing them and the uses of said compounds and compositions for diseases related to sphingosine-1-phosphate (S1P) receptors, predominantly S1P3 receptors. The diseases include cardiovascular diseases, atherosclerosis, cancer, pulmonary oedema, autoimmune disorders and Adult Respiratory Distress Syndrome.
Inventors:
Johannes Bruce
Adrian Peter Yesemann
Astrid Elaine Alewiense
Stephan Leonard Maria Peters
Margot Wilhelmina Beukers
Adrian Peter Yesemann
Astrid Elaine Alewiense
Stephan Leonard Maria Peters
Margot Wilhelmina Beukers
Application Number:
JP2010533676A
Publication Date:
January 27, 2011
Filing Date:
November 13, 2008
Export Citation:
Assignee:
University Reiden
International Classes:
A61K31/381; A61P9/10; A61P11/00; A61P35/00; A61P37/06; A61P43/00; C07D333/36; C07D333/66
Attorney, Agent or Firm:
Kenji Sugimura
Kazuyuki Tomita
Yoichi Iino
Kazuyuki Tomita
Yoichi Iino