Title:
ビシクロ置換ピラゾロン-アゾ誘導体、その調製プロセス及び製薬学的使用
Document Type and Number:
Japanese Patent JP2011509263
Kind Code:
A
Abstract:
The bicyclo-substituted pyrazolon-azo derivatives of formula (I) or pharmaceutical acceptable salts, hydrates or solvates thereof, methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor are disclosed. The definition of substituents in formula (I) are the same as defined in the description.
Inventors:
Tan Pencho
Liu Hee Jun
Tsuen Hao
Chen Yi Chien
Faye Hombo
Wang Shen Lan
Wang LEE
Liu Hee Jun
Tsuen Hao
Chen Yi Chien
Faye Hombo
Wang Shen Lan
Wang LEE
Application Number:
JP2010541680A
Publication Date:
March 24, 2011
Filing Date:
January 04, 2009
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO.,LTD.
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
International Classes:
C07D231/38; A61K31/4152; A61K31/4155; A61K31/4178; A61K31/427; A61K45/00; A61P7/04; A61P7/06; A61P43/00; C07D231/26; C07D403/12; C07D405/04; C07D405/12; C07D409/12; C07D417/12
Domestic Patent References:
| JP2003534257A | 2003-11-18 | |||
| JP2006525352A | 2006-11-09 |
Foreign References:
| WO2007062078A2 | 2007-05-31 | |||
| GB806709A | 1958-12-31 | |||
| WO2007044982A2 | 2007-04-19 | |||
| GB775216A | 1957-05-22 | |||
| WO2007062078A2 | 2007-05-31 | |||
| GB806709A | 1958-12-31 |
Attorney, Agent or Firm:
Xie Takamine
Yasushi Sasaki
Yasushi Sasaki