Title:
分子イメージング先導標的化薬物処理による高治療指数の達成
Document Type and Number:
Japanese Patent JP2011521947
Kind Code:
A
Abstract:
The present disclosure provides methods for treating cancer in a patient in need of such treatment, the method includes prequalifying a patient's therapeutic treatment by performing a molecular imaging procedure to the patient using a labeled biomarker specific for a cancer target at the tumor site; and administering a therapeutic effective amount of a compound comprising a targeting agent linked to a chemotherapeutic or a targeting agent linked to an antibody. Embodiments of the present invention also include compounds and compositions for using such methods.
Inventors:
Corps, Hartmut See
Walsh, Joseph Sea
Chen, Kai
Oak, Dana Lakshmi
Ganga Dermouth, Umesh Bee
Scott, Peter Jay Etch
Chen, gang
Mochala, Vanipee
Walsh, Joseph Sea
Chen, Kai
Oak, Dana Lakshmi
Ganga Dermouth, Umesh Bee
Scott, Peter Jay Etch
Chen, gang
Mochala, Vanipee
Application Number:
JP2011511647A
Publication Date:
July 28, 2011
Filing Date:
June 01, 2009
Export Citation:
Assignee:
Siemens Medical Solutions USA,Inc.
International Classes:
A61K47/48; A61K31/337; A61K31/475; A61K31/573; A61K31/675; A61K31/7008; A61K31/704; A61K39/395; A61K49/00; A61P35/00; C07D207/452; C07D403/14; C07K1/13
Domestic Patent References:
| JP2008515915A | 2008-05-15 | |||
| JP2008510829A | 2008-04-10 | |||
| JP2008515915A | 2008-05-15 | |||
| JP2008510829A | 2008-04-10 |
Foreign References:
| WO2008033557A2 | 2008-03-20 | |||
| WO2008033561A2 | 2008-03-20 | |||
| WO2008033561A2 | 2008-03-20 | |||
| US3769271A | 1973-10-30 | |||
| WO2007018431A2 | 2007-02-15 | |||
| WO2008033557A2 | 2008-03-20 |
Attorney, Agent or Firm:
Iwao Yamaguchi