Title:
α-メラニン形成細胞刺激ホルモンのペプチド類似体
Document Type and Number:
Japanese Patent JP2011521949
Kind Code:
A
Abstract:
Provided herein are stable peptide analogs of the native alpha-melanocyte stimulating hormone (±-MSH) having selectivity for the melanocortin 1 receptor (MC1R). Also provided herein are pharmaceutical preparations of the ±-MSH peptide analogs, as well as methods of using these analogs in the treatment of medical and veterinary conditions involving MC1R.
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Inventors:
Pericone, Michael A.
Zuris, John Lyle
Weeden, Timothy E.
Stefano, James E.
Bread, Clark Kew.
Edling, Andrea Yi.
Zuris, John Lyle
Weeden, Timothy E.
Stefano, James E.
Bread, Clark Kew.
Edling, Andrea Yi.
Application Number:
JP2011511661A
Publication Date:
July 28, 2011
Filing Date:
March 20, 2009
Export Citation:
Assignee:
Genzyme Corporation
International Classes:
C07K7/08; A61K38/22; A61P1/04; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P29/00; A61P35/00; A61P37/06; A61P37/08; C07K14/685; C12N15/09
Foreign References:
| WO2005120588A2 | 2005-12-22 |
Other References:
JPN6013056170; Ｇｅｎｅ ｔｈｅｒａｐｙ． ２００３， Ｖｏｌ．１０， Ｎｏ．４， ｐ．３４８-３５５
JPN6013056171; Ｂｉｏｏｒｇａｎｉｃ ＆ ｍｅｄｉｃｉｎａｌ ｃｈｅｍｉｓｔｒｙ ｌｅｔｔｅｒｓ． ２００４， Ｖｏｌ．１４， Ｎｏ．１， ｐ．２１１-２１５
JPN6013056171; Ｂｉｏｏｒｇａｎｉｃ ＆ ｍｅｄｉｃｉｎａｌ ｃｈｅｍｉｓｔｒｙ ｌｅｔｔｅｒｓ． ２００４， Ｖｏｌ．１４， Ｎｏ．１， ｐ．２１１-２１５
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita