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Title:
キラルアミンの合成
Document Type and Number:
Japanese Patent JP2011525923
Kind Code:
A
Abstract:
The instant invention involves the enantioselective hydrogenation of isomeric N—H imines (N-unsubstituted) using a transition metal based catalyst modified with a chiral phosphine derivative to produce enantiomerically enriched chiral amines.

Inventors:
Oshey, Paul
Goslin, Francis
McWilliams, James, Sea.
Application Number:
JP2011516493A
Publication Date:
September 29, 2011
Filing Date:
June 22, 2009
Export Citation:
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Assignee:
AXYS PHARMACEUTICALS, INC.
International Classes:
C07C209/26; C07C211/29; C07B53/00; C07B61/00
Domestic Patent References:
JPH08508753A1996-09-17
JPH09157228A1997-06-17
JP2001122832A2001-05-08
JP2002255933A2002-09-11
JPH06298780A1994-10-25
Attorney, Agent or Firm:
Yokoyama Isao



 
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