Title:
血小板のインヒビターにより誘発される凝固障害を治療するためのフォン・ヴィレブランド因子または第VIII因子およびフォン・ヴィレブランド因子
Document Type and Number:
Japanese Patent JP2011527301
Kind Code:
A
Abstract:
The present invention relates to a von Willebrand Factor for use in the treatment and/or prevention of a bleeding event associated with a thrombopathy induced by substances inhibiting thrombocytes. Furthermore, the present invention relates to a method of treating and/or preventing a disorder related to a bleeding event associated with a thrombopathy induced by substances inhibiting thrombocytes comprising administering a pharmaceutically effective amount of a von-Willebrand-Factor (vWF) to a patient in need thereof. The present invention also relates to a composition comprising vWF and a composition comprising FVIII for simultaneous, separate or sequential use for use in the treatment and/or prevention of a bleeding event associated with a thrombopathy induced by substances inhibiting thrombocytes.
Inventors:
Gerhard Dick Nighte
Ingo Plugst
Enrique Resa
Torsten Haas
Stephan Zeitler
Ingo Plugst
Enrique Resa
Torsten Haas
Stephan Zeitler
Application Number:
JP2011517038A
Publication Date:
October 27, 2011
Filing Date:
July 10, 2009
Export Citation:
Assignee:
TSE L Bering GMBH
International Classes:
A61K38/00; A61P7/04
Domestic Patent References:
| JPH08208504A | 1996-08-13 | |||
| JPH11510818A | 1999-09-21 |
Other References:
JPN6013038232; Ｐｌａｔｅｌｅｔｓ Ｖｏｌ．７， Ｎｏ．５-６, 1996, ｐ．２８３-２９０
JPN6013038234; Ｔｈｒｏｍｂｏｓｉｓ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１０１， Ｎｏ．３, 2001, ｐ．１５９-１７０
JPN6014013848; 血液・腫瘍科，２０００，Ｖｏｌ．４１，Ｎｏ．３，ｐ．２３８-２４４
JPN6013038234; Ｔｈｒｏｍｂｏｓｉｓ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１０１， Ｎｏ．３, 2001, ｐ．１５９-１７０
JPN6014013848; 血液・腫瘍科，２０００，Ｖｏｌ．４１，Ｎｏ．３，ｐ．２３８-２４４
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi
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