Title:
メトホルミン治療に不適切な患者における糖尿病の治療
Document Type and Number:
Japanese Patent JP2011529945
Kind Code:
A
Abstract:
The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in patients for whom metformin therapy is inappropriate due to intolerability or contraindication against metformin.
Inventors:
Dugi Claus
Grefemodi Eva Urrique
Harper Ruth
Verrehans Jürgen
Grefemodi Eva Urrique
Harper Ruth
Verrehans Jürgen
Application Number:
JP2011521574A
Publication Date:
December 15, 2011
Filing Date:
August 05, 2009
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
A61K45/00; A61K31/4439; A61K31/522; A61P3/00; A61P3/10; A61P43/00
Other References:
JPN6012060559; Ｄｉａｂｅｔｅｓ Ｆｒｏｎｔｉｅｒ Ｖｏｌ．１８，Ｎｏ．６, 2007, ｐ６３６-６４２
JPN6012060560; モダンフィジシャン Ｖｏｌ．２８，Ｎｏ．２, 200802, ｐ１６３-１６５
JPN6012060562; 診断と治療 Ｖｏｌ．９６，Ｎｏ．２, 200802, ｐ３８９-３９０
JPN6012060566; 薬局 Ｖｏｌ．５７，Ｎｏ．９, 2006, ｐ２７３５-２７３９
JPN6012060568; Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｏｌｏｇｙ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｔｈｅｒａｐｅｕｔ Ｖｏｌ．３２５，Ｎｏ．１, 200804, ｐ１７５-１８２
JPN5011011056; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５７，Ｎｏ．Ｓｕｐｐｌ．１, 200806, ｐＡ１５８-Ａ１５９
JPN5011011054; Ｄｉａｂｅｔｏｌｏｇｉａ Ｖｏｌ．５０，Ｎｏ．Ｓｕｐｐｌ．１, 200709, ｐＳ３６７
JPN6012060571; Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．５０，Ｎｏ．２６, 2007, ｐ６４５０-６４５３
JPN5011011055; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５６， Ｎｏ．Ｓｕｐｐｌ．１, 200706, ｐＡ１５６
JPN6012060573; Ｄｉａｂｅｔｅｓ， Ｏｂｅｓｉｔｙ ａｎｄ Ｍｅｔａｂｏｌｉｓｍ Ｖｏｌ．９，Ｎｏ．２, 2007, ｐ１７５-１８５
JPN6012060575; 循環科学 Ｖｏｌ．１７，Ｎｏ．１２, 1997, ｐ１１８６-１１８８
JPN6012060560; モダンフィジシャン Ｖｏｌ．２８，Ｎｏ．２, 200802, ｐ１６３-１６５
JPN6012060562; 診断と治療 Ｖｏｌ．９６，Ｎｏ．２, 200802, ｐ３８９-３９０
JPN6012060566; 薬局 Ｖｏｌ．５７，Ｎｏ．９, 2006, ｐ２７３５-２７３９
JPN6012060568; Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｏｌｏｇｙ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｔｈｅｒａｐｅｕｔ Ｖｏｌ．３２５，Ｎｏ．１, 200804, ｐ１７５-１８２
JPN5011011056; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５７，Ｎｏ．Ｓｕｐｐｌ．１, 200806, ｐＡ１５８-Ａ１５９
JPN5011011054; Ｄｉａｂｅｔｏｌｏｇｉａ Ｖｏｌ．５０，Ｎｏ．Ｓｕｐｐｌ．１, 200709, ｐＳ３６７
JPN6012060571; Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．５０，Ｎｏ．２６, 2007, ｐ６４５０-６４５３
JPN5011011055; Ｄｉａｂｅｔｅｓ Ｖｏｌ．５６， Ｎｏ．Ｓｕｐｐｌ．１, 200706, ｐＡ１５６
JPN6012060573; Ｄｉａｂｅｔｅｓ， Ｏｂｅｓｉｔｙ ａｎｄ Ｍｅｔａｂｏｌｉｓｍ Ｖｏｌ．９，Ｎｏ．２, 2007, ｐ１７５-１８５
JPN6012060575; 循環科学 Ｖｏｌ．１７，Ｎｏ．１２, 1997, ｐ１１８６-１１８８
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa