Title:
アダマンチルベンズアミド化合物
Document Type and Number:
Japanese Patent JP2012509879
Kind Code:
A
Abstract:
Embodiments of the present invention provide adamantyl benzamide derivatives and pharmaceutical compositions comprising adamantyl benzamide derivatives. Methods of use of such compounds and compositions to modulate the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) in a subject are also provided.
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Inventors:
Polsetti, Dharma Rao
Gupta, Sparna
Evdorp, Soren
Gupta, Sparna
Evdorp, Soren
Application Number:
JP2011537550A
Publication Date:
April 26, 2012
Filing Date:
November 17, 2009
Export Citation:
Assignee:
High Point Pharmaceuticals, Limited Liability Company
International Classes:
C07D213/64; A61K31/44; A61K31/50; A61K31/505; A61P27/02; A61P27/06; A61P43/00; C07D213/70; C07D213/71; C07D213/74; C07D237/14; C07D239/42
Domestic Patent References:
| JP2006511570A | 2006-04-06 |
Foreign References:
| WO2008101914A2 | 2008-08-28 |
Other References:
JPN6014008503; Ｊ．Ｍｅｄ．Ｃｈｅｍ．，（２００７），５０（１），ｐ．１４９-１６４
JPN6014008504; Ｂｉｏｏｒｇ．Ｍｅｄ．Ｃｈｅｍ．Ｌｅｔｔ．，（２００６），１６，ｐ．５９５８-５９６２
JPN6014008504; Ｂｉｏｏｒｇ．Ｍｅｄ．Ｃｈｅｍ．Ｌｅｔｔ．，（２００６），１６，ｐ．５９５８-５９６２
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri