Title:
ジフルオロフェニルジアシルヒドラジド誘導体
Document Type and Number:
Japanese Patent JP2012509915
Kind Code:
A
Abstract:
Novel difluorophenyldiacylhydrazide derivatives of the formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in claim 1, are kinase inhibitors and can be used for the treatment of diseases and complaints such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and kidney diseases, generally in any type of fibroses, inflammatory processes, tumours and tumour diseases.
Inventors:
Fuchs, thomas
Glaedler, Ulrich
Bayer, Norbert
Gerikke, rolf
Rank, florian
Glaedler, Ulrich
Bayer, Norbert
Gerikke, rolf
Rank, florian
Application Number:
JP2011537864A
Publication Date:
April 26, 2012
Filing Date:
November 02, 2009
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07C243/38; A61K31/166; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P17/00; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P43/00; C07C241/04
Domestic Patent References:
| JP2008535833A | 2008-09-04 | |||
| JP2007509037A | 2007-04-12 | |||
| JP2008535833A | 2008-09-04 | |||
| JP2007509037A | 2007-04-12 |
Foreign References:
| WO2007093264A1 | 2007-08-23 | |||
| WO2007093264A1 | 2007-08-23 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Noriki Mitsuhashi
Noriki Mitsuhashi