Title:
NaVを発現する細胞株とその使用方法
Document Type and Number:
Japanese Patent JP2012520058
Kind Code:
A
Abstract:
Cells and cell lines that express voltage-gated sodium ion channels (NaV) and methods for using the cells and cell lines are disclosed herein. The NaV-expressing cells and cell lines are useful in cell-based assays, e.g., high throughput screening assays.
Inventors:
Shekdar, Cambies
Olga, Dedova
Olga, Dedova
Application Number:
JP2011547903A
Publication Date:
September 06, 2012
Filing Date:
February 02, 2009
Export Citation:
Assignee:
Chromosel Corporation
International Classes:
C12N5/10; C12Q1/02; C40B30/06; G01N33/15; G01N33/50; G01N37/00; C12N15/09
Domestic Patent References:
| JP2005520540A | 2005-07-14 |
Other References:
MATHES CHRIS: "QPATCH:THE MISSING LINK BETWEEN HTS AND ION CHANNEL DRUG DISCOVERY", COMBINATORIAL CHEMISTRY AND HIGH THROUGHPUT SCREENING, vol. V12 N1, JPN5012007888, January 2009 (2009-01-01), pages 78 - 95, ISSN: 0002669501
ISOM LORT L: "FUNCTIONAL CO-EXPRESSION OF THE BETA-1 AND TYPE IIA ALPHA SUBUNITS OF SODIUM CHANNELS 以下備考", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. V270 N7, JPN5012007889, 1 January 1995 (1995-01-01), US, pages 3306 - 3312, ISSN: 0002669502
ZHANG J-H: "A SIMPLE STATISTICAL PARAMETER FOR USE IN EVALUATION AND VALIDATION OF HIGH THROUGHPUT SCREENING ASS", JOURNAL OF BIOMOLECULAR SCREENING, vol. V4 N2, JPN5012007891, 1 April 1999 (1999-04-01), US, pages 67 - 73, ISSN: 0003131575
ISOM LORT L: "FUNCTIONAL CO-EXPRESSION OF THE BETA-1 AND TYPE IIA ALPHA SUBUNITS OF SODIUM CHANNELS 以下備考", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. V270 N7, JPN5012007889, 1 January 1995 (1995-01-01), US, pages 3306 - 3312, ISSN: 0002669502
ZHANG J-H: "A SIMPLE STATISTICAL PARAMETER FOR USE IN EVALUATION AND VALIDATION OF HIGH THROUGHPUT SCREENING ASS", JOURNAL OF BIOMOLECULAR SCREENING, vol. V4 N2, JPN5012007891, 1 April 1999 (1999-04-01), US, pages 67 - 73, ISSN: 0003131575
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Nao Oda