Title:
抗癌化合物およびこれを含有する医薬組成物
Document Type and Number:
Japanese Patent JP2012527436
Kind Code:
A
Abstract:
The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of 0.698 mg/ml in methanol. The compound may be in the form of a base or an acid addition salt, in particular a pharmaceutically acceptable acid. The compound is a selective Aurora A and B kinase inhibitor and can be used as an anticancer drug.
Inventors:
Cali, Jiyan-Christophe
Schiebe, Michel
Clerque, Francois
Cebo, cecil
Gonteye, Sylvie
Crick, Alan
Rashio, Sylvest
Shio, Laurent
Schiebe, Michel
Clerque, Francois
Cebo, cecil
Gonteye, Sylvie
Crick, Alan
Rashio, Sylvest
Shio, Laurent
Application Number:
JP2012511323A
Publication Date:
November 08, 2012
Filing Date:
May 17, 2010
Export Citation:
Assignee:
SANOFI
International Classes:
C07D471/04; A61K31/122; A61K31/401; A61K31/4184; A61K31/4745; A61P35/00; A61P43/00; C07D207/16; C07D235/26; C07B51/00
Domestic Patent References:
| JP2009501778A | 2009-01-22 | |||
| JP2009501778A | 2009-01-22 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office