Title:
TLR3結合剤
Document Type and Number:
Japanese Patent JP2012532851
Kind Code:
A
Abstract:
The present invention relates to antibodies (e.g. monoclonal antibodies), antibody fragments, and derivatives thereof that specifically bind TLR3, and that optionally further modulate, e.g. inhibit, signaling. The invention also relates to cells producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; pharmaceutical compositions comprising the same; methods of using the antibodies to diagnose, treat or prevent diseases, e.g. autoimmune diseases, inflammatory diseases and the like.
Inventors:
Laurent Gautier
Catherine Massacrier
Yani Morell
Carine Patrell
Catherine Massacrier
Yani Morell
Carine Patrell
Application Number:
JP2012519021A
Publication Date:
December 20, 2012
Filing Date:
July 09, 2010
Export Citation:
Assignee:
INNATE PHARMA
International Classes:
C07K16/28; A61K39/395; A61K45/00; A61P1/16; A61P3/10; A61P11/00; A61P11/06; A61P19/10; A61P29/00; A61P31/00; A61P31/04; A61P37/06; A61P37/08; C07K16/46; C12N5/10; C12N15/02; C12N15/09; C12P21/08
Domestic Patent References:
| JP2008521440A | 2008-06-26 | |||
| JP2012525425A | 2012-10-22 | |||
| JP2008521440A | 2008-06-26 | |||
| JP2012525425A | 2012-10-22 |
Other References:
JPN6014045276; Ｍｏｌｅｃｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．４４, 2007, Ｐ．３６３３-３６４０
JPN6014045273; Ｃｅｌｌｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．２４８, 2007, Ｐ．１０３-１１４
JPN6014045276; Ｍｏｌｅｃｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．４４, 2007, Ｐ．３６３３-３６４０
JPN6014045273; Ｃｅｌｌｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．２４８, 2007, Ｐ．１０３-１１４
JPN6014045276; Ｍｏｌｅｃｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．４４, 2007, Ｐ．３６３３-３６４０
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Manami Sawamoto
Hiroshi Yamazaki
Kenji Tomita
Manami Sawamoto
Previous Patent: Ｃ型肝炎ＮＳ５Ｂポリメラーゼの阻害剤としての置換ピロリジノン、その...
Next Patent: ２型糖尿病における食後高血糖の経頬粘膜治療の方法、および当該治療に...
Next Patent: ２型糖尿病における食後高血糖の経頬粘膜治療の方法、および当該治療に...