Title:
反応性シアニン化合物
Document Type and Number:
Japanese Patent JP2013503209
Kind Code:
A
Abstract:
The invention provides compounds and compositions of Formulas I-VII, and methods of using the compounds. The compounds can be used to prepare dye conjugates that are uniformly and substantially more fluorescent on proteins, nucleic acids or other biopolymers, than conjugates labeled with structurally similar known carbocyanine dyes. In addition to having more intense fluorescence emission than structurally similar dyes at virtually identical wavelengths, and decreased artifacts in their absorption spectra upon conjugation to biopolymers, the compounds can have greater photostability and/or higher absorbance (extinction coefficients) at the wavelength(s) of peak absorbance than such structurally similar dyes.
More Like This:
Inventors:
Corona caesar
Claubert diet
McDougall mark
Claubert diet
McDougall mark
Application Number:
JP2012527968A
Publication Date:
January 31, 2013
Filing Date:
August 31, 2010
Export Citation:
Assignee:
Promega Corporation
International Classes:
C07D519/00; C09B23/00; G01N21/64
Domestic Patent References:
| JP2000321704A | 2000-11-24 |
Foreign References:
| WO2002026891A1 | 2002-04-04 | |||
| US2398999A | 1946-04-23 | |||
| DE10159078A1 | 2003-06-05 |
Other References:
JPN5012018618; ＵＳＨＥＮＫＯ: 'ＣＹＡＮＩＮＥ ＤＹＥＳ' ＵＫＲＡＩＮＳＫＩＩ ＫＨＩＭＩＣＨＥＳＫＩＩ ＺＨＵＲＮＡＬ ＶＯＬ． ２１, 19550101, ＰＡＧＥＳ ７４４-７４９
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Shimura
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Shimura