Title:
前立腺癌の診断方法および診断キット
Document Type and Number:
Japanese Patent JP2013531997
Kind Code:
A
Abstract:
The invention relates to methods and kits for the diagnosis of prostate cancer in a subject, for assessing or monitoring the response to a therapy in a subject having prostate cancer (PCa) or for monitoring the progression of prostate cancer (PCa) based on the detection of alteration in the expression levels of at least one gene selected from the group of PCA3, PSMA and PSGR. The invention relates as well to methods for assessing whether a subject has to be subjected to a prostate biopsy, said subject having a serum PSA range within 4-10 ng/mL.
Inventors:
Dollar, Andreas
Rigaau Resina, Marina
Morote Robles, Juan
Aval Posada, Miguel
Levent Spuig Hanel, Haume
Rigaau Resina, Marina
Morote Robles, Juan
Aval Posada, Miguel
Levent Spuig Hanel, Haume
Application Number:
JP2013519101A
Publication Date:
August 15, 2013
Filing Date:
July 14, 2011
Export Citation:
Assignee:
Fundacio Instituto de Reserca Hospital Universitari Val de Bron, Fundacio Privada
International Classes:
C12Q1/68; G01N33/68; C12N15/09
Other References:
JPN6015031487; 泌尿器外科 Ｖｏｏ．２１， Ｎｏ．１０, 2008, ｐｐ．１３４５-１３４９
JPN6015031488; Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．５９， Ｎｏ．２３, 1999, ｐｐ．５９７５-５９７９
JPN6015031489; Ｕｒｏｌｏｒｙ Ｖｉｅｗ Ｖｏｌ．３， Ｎｏ．４, 2005, ｐｐ．８３-９０
JPN6015031490; Ｕｒｏｌｏｇｙ Ｖｉｅｗ Ｖｏｌ．８， Ｎｏ．２, 201003, ｐｐ．９７-１０３
JPN6015031491; Ｊ Ｃｅｌｌ Ｂｉｏｃｈｅｍ． Ｖｏｌ．９６， Ｎｏ．５, 2005, ｐｐ．１０３４-１０４８
JPN6015031492; Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．６０， Ｎｏ．２３, 2000, ｐｐ．６５６８-６５７２
JPN6015031493; Ｕｒｏｌｏｇｙ Ｖｉｅｗ Ｖｏｌ．４， Ｎｏ．１, 2006, ｐｐ．７６-８２
JPN6015031494; 癌と化学療法 Ｖｏｌ．３１， Ｎｏ．７, 2004, ｐｐ．１００８-１０１４
JPN6015031495; 泌尿器外科 Ｖｏｌ．１８， Ｎｏ．８, 2005, ｐｐ．８７７-８８０
JPN6015031497; Ｈｅａｒｔ Ｖｏｌ．９１， Ｎｏ．５, 2005, ｐｐ．６１３-６１７
JPN6015031499; Ｃｌｉｎ Ｃｈｅｍ． Ｖｏｌ．４５， Ｎｏ．５, 1999, ｐｐ．６５１-６５８
JPN6015031502; Ｃｌｉｎ Ｃｈｅｍ． Ｖｏｌ．４１， Ｎｏ．８ Ｐｔ ２, 1995, ｐｐ．１２４８-１２５５
JPN6015031503; Ｊ Ｎｅｕｒｏｔｒａｕｍａ Ｖｏｌ．２６， Ｎｏ．９, 2009, ｐｐ．１４７９-１４８７
JPN6015031488; Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．５９， Ｎｏ．２３, 1999, ｐｐ．５９７５-５９７９
JPN6015031489; Ｕｒｏｌｏｒｙ Ｖｉｅｗ Ｖｏｌ．３， Ｎｏ．４, 2005, ｐｐ．８３-９０
JPN6015031490; Ｕｒｏｌｏｇｙ Ｖｉｅｗ Ｖｏｌ．８， Ｎｏ．２, 201003, ｐｐ．９７-１０３
JPN6015031491; Ｊ Ｃｅｌｌ Ｂｉｏｃｈｅｍ． Ｖｏｌ．９６， Ｎｏ．５, 2005, ｐｐ．１０３４-１０４８
JPN6015031492; Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．６０， Ｎｏ．２３, 2000, ｐｐ．６５６８-６５７２
JPN6015031493; Ｕｒｏｌｏｇｙ Ｖｉｅｗ Ｖｏｌ．４， Ｎｏ．１, 2006, ｐｐ．７６-８２
JPN6015031494; 癌と化学療法 Ｖｏｌ．３１， Ｎｏ．７, 2004, ｐｐ．１００８-１０１４
JPN6015031495; 泌尿器外科 Ｖｏｌ．１８， Ｎｏ．８, 2005, ｐｐ．８７７-８８０
JPN6015031497; Ｈｅａｒｔ Ｖｏｌ．９１， Ｎｏ．５, 2005, ｐｐ．６１３-６１７
JPN6015031499; Ｃｌｉｎ Ｃｈｅｍ． Ｖｏｌ．４５， Ｎｏ．５, 1999, ｐｐ．６５１-６５８
JPN6015031502; Ｃｌｉｎ Ｃｈｅｍ． Ｖｏｌ．４１， Ｎｏ．８ Ｐｔ ２, 1995, ｐｐ．１２４８-１２５５
JPN6015031503; Ｊ Ｎｅｕｒｏｔｒａｕｍａ Ｖｏｌ．２６， Ｎｏ．９, 2009, ｐｐ．１４７９-１４８７
Attorney, Agent or Firm:
Konno Akio
Minoru Inami
Takeyasu Ito
Keisei Tamura
Minoru Inami
Takeyasu Ito
Keisei Tamura