Title:
肝疾患治療用の医薬組成物
Document Type and Number:
Japanese Patent JP2014508785
Kind Code:
A
Abstract:
The disclosure provides a pharmaceutical composition for retarding liver cancer growth, improving liver function, liver fibrosis, liver cirrhosis and liver inflammation, and promoting damaged liver regeneration, including: a proanthocyanidin with an effective amount; and a pharmaceutically acceptable carrier or salt, wherein the monomer units of the proanthocyanidin have the following formula. In the formula, when R 1 is OCH 3 , R 2 is OH and R 3 is H, when R 1 is OH, R 2 is H and R 3 is H, when R 1 is OH, R 2 is OH and R 3 is H, or when R 1 is OH, R 2 is OH and R 3 is OH, and R 4 is 3-(±)-OH, 3-(²)-OH, 3-(±)-O-sugar or 3-(²)-O-sugar.
Inventors:
Zhang Feng Feng
Ma Shunken
Kuniyoshi Yang
Hayashi
Hayashi Ken
Huang Kaibun
Ma Shunken
Kuniyoshi Yang
Hayashi
Hayashi Ken
Huang Kaibun
Application Number:
JP2014500226A
Publication Date:
April 10, 2014
Filing Date:
March 22, 2011
Export Citation:
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
International Classes:
A61K31/353; A61K36/00; A61K36/18; A61K36/73; A61P1/16; A61P35/00
Domestic Patent References:
| JP2010155840A | 2010-07-15 | |||
| JP2009242374A | 2009-10-22 | |||
| JP2008156265A | 2008-07-10 | |||
| JP2008195672A | 2008-08-28 |
Foreign References:
| CN1443533A | 2003-09-24 | |||
| WO2005013970A1 | 2005-02-17 |
Other References:
JPN6014050101; Ｍｕｔａｔ． Ｒｅｓ．， ２００５， Ｖｏｌ．５７９， Ｎｏ．１-２， ｐ．８１-１０６
Attorney, Agent or Firm:
Kyuichi Ueki
Hisahiko Ueki
Tadashi Sugakawa
Hiroaki Ito
Akemi Takeoka
Hisahiko Ueki
Tadashi Sugakawa
Hiroaki Ito
Akemi Takeoka
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