Title:
抗神経成長因子抗体並びに前記の製造及び使用方法
Document Type and Number:
Japanese Patent JP2014519317
Kind Code:
A
Abstract:
A method of preparing an antibody suitable for use in a feline is provided. Also provided are chimeric and felinised antibodies which specifically bind to feline neuronal growth factor (NGF) and neutralise the ability of feline NGF to bind to the p75 or TrkA feline NGF receptor. The invention extends to nucleic acids encoding same and to methods of treating pain and arthritis in a feline using said antibodies and/or nucleic acids.
Inventors:
ゲアリング David
Application Number:
JP2014509818A
Publication Date:
August 14, 2014
Filing Date:
May 08, 2012
Export Citation:
Assignee:
エヌヴィーアイピー Proprietary Limited
International Classes:
C12N15/09; A61K31/7088; A61K35/12; A61K35/76; A61K39/395; A61K45/00; A61K48/00; A61P17/04; A61P19/02; A61P25/00; A61P25/04; A61P29/00; A61P35/00; C07K16/22; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Domestic Patent References:
| JP2008500274A | 2008-01-10 | |||
| JP2008542439A | 2008-11-27 | |||
| JP2006525960A | 2006-11-16 | |||
| JP2008518619A | 2008-06-05 | |||
| JP2005514063A | 2005-05-19 |
Foreign References:
| WO2010027488A2 | 2010-03-11 | |||
| WO2012024650A2 | 2012-02-23 | |||
| WO2010079850A2 | 2010-07-15 | |||
| WO2009088065A1 | 2009-07-16 |
Other References:
NEUROPEPTIDES, vol. 43, no. 5, JPN6016009983, 2009, pages 363 - 369, ISSN: 0003676404
DRUG METABOLISM AND DISPOSITION, vol. 27, JPN6017042154, 1999, pages 21 - 25, ISSN: 0003676405
DRUG METABOLISM AND DISPOSITION, vol. 27, JPN6017042154, 1999, pages 21 - 25, ISSN: 0003676405
Attorney, Agent or Firm:
辻居 Koichi
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Yamasaki Kazuo
Ichikawa Azalea
Toshio Takizawa
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Yamasaki Kazuo
Ichikawa Azalea
Toshio Takizawa