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Title:
［（３−ヒドロキシピリジン−２−カルボニル）アミノ］アルカン酸、エステル及びアミドの製造方法
Document Type and Number:
Japanese Patent JP2014522409
Kind Code:
A
Abstract:
The present invention relates to a process for preparing N-[[5-(3- chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-glycine (compound (5)), from the intermediates 5-(3-chlorophenyl)-3-chloro-2- pyridinecarbonitrile (compound (1)), 5-(3-chlorophenyl)-3-methoxy-2- pyridinecarbonitrile (compound (2)), 5-(3-chlorophenyl)-3-hydroxy-2- pyridinecarboxylic acid (compound (3)). Compound (5) is an intermediate in the preparation of prolyl hydroxylase inhibitors.

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Inventors:
Christopher M. run シエル
Boris Gorin
Jean オウデネス
Craig Edward Dixon
Alan クイグボ ル
James デンスモア Glass
John Michael ジャヌスズ
Application Number:
JP2014514536A
Publication Date:
September 04, 2014
Filing Date:
June 05, 2012
Export Citation:
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Assignee:
アケビア Therapeutics In condominium lei テッド AKEBIA THERAPEUTICS INC.
International Classes:
C07D213/81; A61P43/00; A61K31/4418; C07B61/00
Domestic Patent References:
JP2009541486A2009-11-26
JP2014522410A2014-09-04
Foreign References:
US3655679A1972-04-11
WO2010113942A12010-10-07
Attorney, Agent or Firm:
Ishikawa 徹



 
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