Title:
未分化リンパ腫キナーゼ（ＡＬＫ）阻害剤としてのインドロキノロン化合物
Document Type and Number:
Japanese Patent JP2017506673
Kind Code:
A
Abstract:
本明細書に開示されるのは、特定のインドロキノロン（ｉｎｄｏｌｏｑｕｉｎｏｌｏｎｅ）化合物、それらの調製方法、それらの医薬組成物、及びそれらの使用、例えばＡＬＫ阻害剤としてのそれらの使用である。
Inventors:
Jien Yong Chen
Zhou Yun Loan
Xiaom On Warn
Guo Mean
Yarn Dage In
The Aurean Lean
Gene Yui
Chiang Shui
Riu Riu
Lone Chuwanbai
Chao-Ye Yan
Donna McKee Chan
Zhou Yun Loan
Xiaom On Warn
Guo Mean
Yarn Dage In
The Aurean Lean
Gene Yui
Chiang Shui
Riu Riu
Lone Chuwanbai
Chao-Ye Yan
Donna McKee Chan
Application Number:
JP2016571453A
Publication Date:
March 09, 2017
Filing Date:
February 27, 2014
Export Citation:
Assignee:
Gian Su Ascentage Biomed Development Inc.
International Classes:
C07D471/04; A61K31/475; A61K31/496; A61K31/5377; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
| JP2013107869A | 2013-06-06 | |||
| JP2013107869A | 2013-06-06 |
Foreign References:
| DE2113343A1 | 1972-09-21 | |||
| DE2113343A1 | 1972-09-21 |
Other References:
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WANG,L. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.20, JPN6017045209, 2012, pages 4820 - 4829
MEI,Z. ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. Vol.56, JPN6017045210, 2013, pages 1431 - 1442
SAYED,I.E. ET AL., MED CHEM RES, vol. Vol.21, JPN6017045211, 2012, pages 4219 - 4229
CHEN,Y. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.12, JPN6017045204, 2004, pages 6539 - 6546
LU.W. ET AL., MED CHEM RES, vol. Vol.22, JPN6017045205, 2013, pages 4492 - 4504
BERGMAN,J. ET AL., TETRAHEDRON, vol. Vol.59, JPN6017045206, 2003, pages 1033 - 1048
SAYED,I.E. ET AL., J. MED. CHEM., vol. Vol.52, JPN6017045207, 2009, pages 2979 - 2988
VOUTE,N. ET AL., ORG. BIOMOL. CHEM., vol. Vol.8, JPN6017045208, 2010, pages 442 - 450
WANG,L. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.20, JPN6017045209, 2012, pages 4820 - 4829
MEI,Z. ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. Vol.56, JPN6017045210, 2013, pages 1431 - 1442
SAYED,I.E. ET AL., MED CHEM RES, vol. Vol.21, JPN6017045211, 2012, pages 4219 - 4229
LU.W. ET AL., MED CHEM RES, vol. Vol.22, JPN6017045205, 2013, pages 4492 - 4504
BERGMAN,J. ET AL., TETRAHEDRON, vol. Vol.59, JPN6017045206, 2003, pages 1033 - 1048
SAYED,I.E. ET AL., J. MED. CHEM., vol. Vol.52, JPN6017045207, 2009, pages 2979 - 2988
VOUTE,N. ET AL., ORG. BIOMOL. CHEM., vol. Vol.8, JPN6017045208, 2010, pages 442 - 450
WANG,L. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.20, JPN6017045209, 2012, pages 4820 - 4829
MEI,Z. ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. Vol.56, JPN6017045210, 2013, pages 1431 - 1442
SAYED,I.E. ET AL., MED CHEM RES, vol. Vol.21, JPN6017045211, 2012, pages 4219 - 4229
CHEN,Y. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.12, JPN6017045204, 2004, pages 6539 - 6546
LU.W. ET AL., MED CHEM RES, vol. Vol.22, JPN6017045205, 2013, pages 4492 - 4504
BERGMAN,J. ET AL., TETRAHEDRON, vol. Vol.59, JPN6017045206, 2003, pages 1033 - 1048
SAYED,I.E. ET AL., J. MED. CHEM., vol. Vol.52, JPN6017045207, 2009, pages 2979 - 2988
VOUTE,N. ET AL., ORG. BIOMOL. CHEM., vol. Vol.8, JPN6017045208, 2010, pages 442 - 450
WANG,L. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. Vol.20, JPN6017045209, 2012, pages 4820 - 4829
MEI,Z. ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. Vol.56, JPN6017045210, 2013, pages 1431 - 1442
SAYED,I.E. ET AL., MED CHEM RES, vol. Vol.21, JPN6017045211, 2012, pages 4219 - 4229
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kumi Kitamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kumi Kitamura