Title:
ＰＤ−１／ＰＤ−Ｌ１およびＣＤ８０（Ｂ７−１）／ＰＤ−Ｌ１タンパク質／タンパク質相互作用の大環状阻害剤
Document Type and Number:
Japanese Patent JP2017536330
Kind Code:
A
Abstract:
本開示は、ＰＤ−１/ＰＤ−Ｌ１およびＰＤ−Ｌ１/ＣＤ８０タンパク質/タンパク質の相互作用を阻害する新規大環状ペプチドを提供するものであり、こうして癌および感染症含めた様々な疾患を緩和するのに有用である。
More Like This:
Inventors:
Michael Matthew Miller
Claudio Mappelli
Martin Patrick Allen
Michael s bowshire
Eric P. Gillis
David Earl Langley
Eric Maru
Mode a polier
Nishito Sangvi
Lee Chiang Soon
Daniel Jay Tenney
Cap-Sung Yeun
Julian Jou
Kevin W. Gilman
Jiao Chien
Catherine A. Grant-Young
Paul Michael Scola
Lyndon A. M. Cornelius
Claudio Mappelli
Martin Patrick Allen
Michael s bowshire
Eric P. Gillis
David Earl Langley
Eric Maru
Mode a polier
Nishito Sangvi
Lee Chiang Soon
Daniel Jay Tenney
Cap-Sung Yeun
Julian Jou
Kevin W. Gilman
Jiao Chien
Catherine A. Grant-Young
Paul Michael Scola
Lyndon A. M. Cornelius
Application Number:
JP2017514316A
Publication Date:
December 07, 2017
Filing Date:
September 11, 2014
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07K7/50; A61K38/12; A61K45/00; A61P31/00; A61P31/04; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P35/00; A61P35/04; A61P37/04; A61P43/00
Domestic Patent References:
| JP2013534922A | 2013-09-09 | |||
| JP2000229998A | 2000-08-22 | |||
| JP2001504819A | 2001-04-10 | |||
| JPH10507776A | 1998-07-28 | |||
| JP2012058092A | 2012-03-22 |
Foreign References:
| WO2013144704A1 | 2013-10-03 | |||
| WO2012074130A1 | 2012-06-07 | |||
| WO2009114335A2 | 2009-09-17 |
Other References:
MOL. MED. REP. (2012) VOL.6, ISSUE 3, P.553-557, JPN6018002569, ISSN: 0003869225
ACS CHEM. BIOL. (2012) VOL.7, ISSUE 3, P.607-613, JPN6018002566, ISSN: 0003869226
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2013) VOL.1(SUPPL 1), O24, JPN6018033950, ISSN: 0003869227
DIFFERDING E., AUNP-12 - A NOVEL PEPTIDE THERAPEUTIC TARGETING PD-1 IMMUNE CHECKPOINT PATHWAY FOR CANCER IMMUNOTHER, vol. pp.1-12, JPN7018002951, 26 February 2014 (2014-02-26), ISSN: 0003869228
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011) VOLUME 2011, ARTICLE ID 451694, PP.1-9, JPN6018033949, ISSN: 0003869224
ACS CHEM. BIOL. (2012) VOL.7, ISSUE 3, P.607-613, JPN6018002566, ISSN: 0003869226
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2013) VOL.1(SUPPL 1), O24, JPN6018033950, ISSN: 0003869227
DIFFERDING E., AUNP-12 - A NOVEL PEPTIDE THERAPEUTIC TARGETING PD-1 IMMUNE CHECKPOINT PATHWAY FOR CANCER IMMUNOTHER, vol. pp.1-12, JPN7018002951, 26 February 2014 (2014-02-26), ISSN: 0003869228
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011) VOLUME 2011, ARTICLE ID 451694, PP.1-9, JPN6018033949, ISSN: 0003869224
Attorney, Agent or Firm:
Samejima Mutsumi
Nagatoshi Shinagawa
Kure Hidenori
Mizuhara Masahiro
Nagatoshi Shinagawa
Kure Hidenori
Mizuhara Masahiro
Previous Patent: ９，９，１０，１０−テトラフルオロ−９，１０−ジヒドロフェナントレ...
Next Patent: エチレンジアルキルホスフィン酸、−エステル及び−塩の製造方法並びに...
Next Patent: エチレンジアルキルホスフィン酸、−エステル及び−塩の製造方法並びに...