Title:
IMMUNOMAGNETIC COMPOSITION, METHOD FOR PREPARING THE SAME, METHOD FOR USING THE SAME, AND CANCER TREATMENT KIT
Document Type and Number:
Japanese Patent JP2018188435
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an immunomagnetic composition.SOLUTION: An immunomagnetic composition 100 comprises: a core layer 110; a shell layer 120 which consists of a composite in which fucoidan, oxidized dextran and super-paramagnetic iron oxide nanoparticle are bound by hydrophobic interaction, and covers the core layer 110; and an external layer 130 containing at least one antibody 131, in which the antibody 131 is grafted outside the shell layer 120 and constitutes the external layer 130. Thus the immunomagnetic composition 100 can be used for preparing an anti-cancer agent.SELECTED DRAWING: Figure 1
Inventors:
SHYU WOEI-CHERNG
CHEN SAN-YUAN
JIANG ZHISHENG
HSIEH CHIA-HUNG
LIN YU-JUNG
TSAI CHANG-HAI
CHEN SAN-YUAN
JIANG ZHISHENG
HSIEH CHIA-HUNG
LIN YU-JUNG
TSAI CHANG-HAI
Application Number:
JP2018088193A
Publication Date:
November 29, 2018
Filing Date:
May 01, 2018
Export Citation:
Assignee:
UNIV CHINA MEDICAL
International Classes:
A61K47/69; A61K9/51; A61K31/737; A61K36/03; A61K39/395; A61K45/00; A61K47/02; A61K47/61; A61P35/00; A61P35/04; A61P37/02; A61P43/00; B82Y5/00; B82Y40/00
Attorney, Agent or Firm:
Masaki Hattori