Title:
TRANSFORMANTS AND METHODS FOR PRODUCING 3-HYDROXYPROPIONIC ACID
Document Type and Number:
Japanese Patent JP2019165636
Kind Code:
A
Abstract:
To provide transformants of S. pombe which can produce 3-HP with high productivity without requiring alkaline neutralization, and methods for producing 3-HP by culturing the transformants.SOLUTION: The invention provides a transformant of Schizosaccharomyces pombe, to which a gene encoding malonyl-CoA reductase, a gene encoding acetyl-CoA carboxylase, a gene encoding pyruvate oxidase, and a gene encoding acetyl-CoA synthetase are introduced, or a gene encoding malonyl-CoA reductase, a gene encoding acetyl-CoA carboxylase and genes capable of forming a pyruvate dehydrogenase complex are introduced, where the pyruvate oxidase is an enzyme that catalyzes a reaction to form acetic acid from pyruvic acid and water.SELECTED DRAWING: None
Inventors:
URUSHIBARA MASAHIRO
TAKEGAWA KAORU
SUYAMA AKIKO
TAKEGAWA KAORU
SUYAMA AKIKO
Application Number:
JP2016159034A
Publication Date:
October 03, 2019
Filing Date:
August 12, 2016
Export Citation:
Assignee:
AGC INC
UNIV KYUSHU
UNIV KYUSHU
International Classes:
C12N1/19; C12P7/42; C12P7/52
Attorney, Agent or Firm:
Sumio Tanai
Masatake Shiga
Suzuki Mitsuyoshi
Noriko Yanai
Masatake Shiga
Suzuki Mitsuyoshi
Noriko Yanai